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Big Ten CRC Jessen Award supports research on digital intervention for prostate cancer survivors

May 1, 2025: 

Right: Roberto Benzo, PhD Left: David Cella, PhD

The Big Ten Cancer Research Consortium Foundation announces that Roberto Benzo, PhD, of The Ohio State University, and David Cella, PhD, of Northwestern University, have been awarded the $65,000 Kenneth and Verna Mae Jessen Award for their research proposal, “Development of a Digital Intervention to Promote Cardiovascular Health in Prostate Cancer Survivors: A Cardio-Oncology Approach.”

The project was one of 21 proposals submitted for funding consideration through an RFP announced by the Big Ten CRC in late 2024. Proposals were reviewed by a committee of Big Ten CRC leaders and peer investigators, chaired by Kari Wisinski, MD, of the University of Wisconsin.

Drs. Benzo and Cella are collaborating on this study with Peter Washington, PhD, of the University of California San Francisco. Co-investigators at The Ohio State University include Steven K. Clinton, MD, PhD; Adam Potter, MD, PhD; and Soledad Fernandez, PhD.

Cardiovascular disease is the leading cause of non-cancer mortality among cancer survivors, particularly those with prostate cancer undergoing androgen deprivation therapy, which significantly increases cardiovascular risk. Despite these known risks, there are no widely adopted digital solutions to proactively monitor cardiovascular health and guide tailored interventions in this vulnerable population.

The proposed project seeks to develop and evaluate a mobile health intervention, “mHealthy Hearts,” to enhance cardiovascular health monitoring and promote physical activity engagement among prostate cancer survivors.

The Big Ten CRC Foundation established the Kenneth and Verna Mae Jessen Award to support basic, correlative, clinical, or population science oncology research based at a Big Ten CRC institution. The award is made possible through the generous support of the Verna Mae Jessen Trust.

The Jessen family’s passion for oncology research stems from their long history with cancer. Several members of the family, including Kenneth, Verna Mae, and two of their siblings fought battles with cancer.

“Our family recognizes the great strides already made and the importance of continuing to fund cancer research,” said Tom Jensen, nephew of Kenneth and Verna Mae Jessen and administrator of the Verna Mae Jessen Trust.

About the Big Ten Cancer Research Consortium: The Big Ten Cancer Research Consortium was created in 2013 to transform the conduct of cancer research through collaborative clinical trials and observational studies that seek to improve the lives of cancer patients in the diverse communities we serve by leveraging the scientific and clinical expertise of Big Ten universities. The Big Ten Cancer Research Consortium creates a unique team research culture to drive science rapidly from ideas to treatment and prevention. Within this innovative environment, today’s research leaders collaborate with and mentor the research leaders of tomorrow. Since its founding, the Big Ten CRC has activated nearly 40 clinical trials across a wide range of cancer types, more than 1,000 participants have enrolled in Big Ten CRC studies, and more than 500 researchers have joined Big Ten CRC Clinical Trial Working Groups.

About the Big Ten Conference: The Big Ten Conference is an association of world-class universities whose member institutions share a common mission of research, graduate, professional and undergraduate teaching and public service. Founded in 1896, the Big Ten has sustained a comprehensive set of shared practices and policies that enforce the priority of academics in the lives of students competing in intercollegiate athletics and emphasize the values of integrity, fairness and competitiveness. The broad-based programs of the 18 Big Ten institutions provide direct financial support for more than 11,000 participation opportunities on 350 teams in 42 different sports. The Big Ten sponsors 28 official conference sports, 14 for men and 14 for women. For more information, visit www.bigten.org.

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April 30, 2025:  In this month’s Across the Consortium, the Big Ten Cancer Research Consortium spotlights advancements in colorectal cancer research, collaborative efforts in prostate cancer studies, recent research grant recipients, new podcast episodes, lung cancer research and prevention initiatives, brain cancer discoveries, leadership transitions, and the critical role of clinical trials. University of Illinois Cancer Center UI Health surgeon Gerald Gantt, Jr., who specializes in the treatment of colon and rectal cancers, was featured on radio and TV shows in Chicago and Wisconsin during Colorectal Cancer Awareness Month in March. In Chicago, the WVON Morning Show with Rufus Williams featured an extended conversation with him about screening and prevention. Read More

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March 25, 2025:  The Indianapolis Business Journal (IBJ) and Inside Indiana Business (IIB) recently interviewed Brian Stemme, CEO of Hoosier Cancer Research Network, which serves as the consortium’s administrative headquarters, for separate pieces highlighting the Big Ten Cancer Research Consortium. The IBJ also interviewed Dr. Nabil Adra, a genitourinary medical oncologist at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center and Big Ten CRC Steering Committee representative for Indiana University. Both pieces tied into local events this month, as the city of Indianapolis hosted the Big Ten men’s and women’s basketball tournaments. The IBJ article can be found here: Read More

Across the Consortium: March 2025

March 17, 2025:  We are thrilled to reintroduce Across the Consortium, a monthly article showcasing the latest news and events from our member institutions. In this edition, we proudly add our newest member, Fred Hutchinson Cancer Center, which serves as the cancer program for UW Medicine—the University of Washington’s health system—joining our consortium of now 16 institutions. Read More

BTCRC-GU15-023 presented at ASCO GU

February 13, 2025: A correlative study related to the Big Ten Cancer Research Consortium (Big Ten CRC) clinical trial, BTCRC-GU15-023, titled, “Phase Ib/II Study of Concurrent Durvalumab And Radiation Therapy (DUART) Followed by Adjuvant Durvalumab in Patients with Urothelial Cancer (T2-4 N0-2 M0) of the Bladder,” will be presented as a poster presentation at American Society of Clinical Oncology® (ASCO) Genitourinary Cancers Symposium 2025 by Adriana S. Ramos-Medero of Ponce Health Sciences University School of Medicine. Read More

Big Ten Cancer Research Consortium adds Fred Hutch Cancer Center

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BTCRC-GI21-500 presented at ASCO GI 2025

January 22, 2025:  A Big Ten CRC study, BTCRC-GI21-500, will be presented as a Trials in Progress poster at the American Society of Clinical Oncology® (ASCO) Gastrointestinal Cancers Symposium 2025 in San Francisco. This study is led by Ashish Manne, MBBS, of The Ohio State University. Read More

BTCRC-LYM20-463 abstract poster presented at ASH 2024

December 17, 2024:  A Big Ten Cancer Research Consortium trial, BTCRC-LYM20-463, titled, "A Phase I/II Study of Tazemetostat Combined with Abbreviated Rituximab/Bendamustine Therapy for High Tumor Burden Follicular Lymphoma in Frontline Treatment: A Big Ten Cancer Research Consortium Study," was presented as a poster presentation at the 2024 American Society of Hematology Annual Meeting on December 9, 2024.  Congratulations to Vaishalee P Kenkre, MD, of the University of Wisconsin School of Medicine and Public Health, Andrew M Evens, DO, MBA, MSc, of Rutgers Cancer Institute and all co-authors! Read More

BTCRC-BRE16-042 abstract accepted for a poster presentation at SABCS 2024

December 6, 2024: A Big Ten Cancer Research Consortium (Big Ten CRC) trial titled, “A Phase II Study of Pembrolizumab Plus Fulvestrant in Hormone Receptor Positive, HER-2 Negative Advanced/Metastatic Breast Cancer Patients: Big Ten Cancer Research Consortium BTCRC-BRE16-042” has been accepted as a poster presentation (P2-07-21) at the 2024 San Antonio Breast Cancer Symposium on December 11, 2024 from 5:30 pm – 7:30 pm. Congratulations to all co-authors and study teams involved in the study! Read More

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