July 14, 2015: The Big Ten Cancer Research Consortium (Big Ten CRC) was established in 2013 to provide new opportunities for collaborative, investigator-initiated research at Big Ten cancer centers. Faculty at Big Ten CRC member institutions have been actively involved throughout the consortium’s development, resulting in the achievement of many milestones for the Big Ten CRC. The Big Ten CRC opened its first clinical trial recently, and numerous other trials and concepts are in the pipeline. Read More
July 1, 2015: A conversation with Douglas Yee, MD, director, and Jeffrey Miller, MD, deputy director, of the Masonic Cancer Center, University of Minnesota, which is a member of the Big Ten Cancer Research Consortium (Big Ten CRC): Q: How do you think cancer research will change in the next 10-20 years? Douglas Yee, MD (DY): In the coming years, patients will see more precise and personalized therapies due to targeted tumor profiling. Personalized medicine is the wave of the future, and we’re excited to have some incredibly strong researchers in areas like bone marrow transplant, NK cell research, and cell products. Jeff Miller, MD (JM): Here at the Masonic Cancer Center, we are addressing this shift by investing... Read More
June 22, 2015: This month, we draw attention to significant milestones and achievements at Big Ten Cancer Research Consortium (Big Ten CRC) member institutions: From the launch of the Big Ten CRC's first clinical trial at the University of Illinois, to Dr. Max Wicha's appointment to the National Cancer Advisory Board by President Obama; from significant funding to Big Ten CRC institutions by the Howard Hughes Medical Institute and the American Cancer Society, to the University of Nebraska's partnership with IBM on the Watson Genomic Analytics program. We celebrate the groundbreaking of the Michigan State University Grand Rapids Research Center, and we highlight advances in research Across the Consortium. Read More
June 5, 2015: Ruth M. O'Regan, MD, has joined the Big Ten Cancer Research Consortium Steering Committee, representing the University of Wisconsin Carbone Cancer Center. The committee, composed of one researcher from each member institution, meets on a regular basis to review activities of the consortium and decide matters of policy. The committee determines the criteria for approving concepts for development with the Big Ten CRC. Read More
June 1, 2015: A conversation with Kenneth H. Cowan, MD, PhD, director of Fred & Pamela Buffett Cancer Center (University of Nebraska), which is a member of the Big Ten Cancer Research Consortium (Big Ten CRC): Q: How do you think cancer research will change in the next 10 or 20 years? Cancer research will move toward precision cancer medicine. Using genomics and other new diagnostic tools, we will be able to employ precision medicine to customize therapies, care for each cancer patient individually, and ultimately improve outcomes. We are investing more efforts into personalized treatments including a partnership with IBM to conduct early testing... Read More
May 21, 2015: The Big Ten Cancer Research Consortium (Big Ten CRC) announces the opening of a clinical trial for patients with metastatic kidney cancer. The study, known as BTCRC-GU14-003, involves a combination of pembrolizumab, a PD-1 inhibitor, with bevacizumab, a therapy that targets blood vessel formation in tumors, for the treatment of patients with metastatic kidney cancer. The study is now open at the University of Illinois Cancer Center in Chicago. Additional member sites within the Big Ten Cancer Research Consortium will open the trial in the... Read More
May 1, 2015: During National Melanoma/Skin Cancer Detection and Prevention Month, Big Ten Cancer Research Consortium member institutions are helping to raise awareness of skin cancers while advancing scientific knowledge through research that is making a difference in the lives of patients. Carrie Best is one of those patients. Diagnosed with Merkel cell carcinoma, a rare cancer (only 2,000 cases were diagnosed in the U.S. in 2014), Best was determined to learn all she could about the disease and her options for treatment. She contacted physicians and researchers worldwide, and soon began treatment in Ohio. However, early in her treatment, Best learned that her cancer was not responding, and she was told her odds of recovery were less than one percent. Read More
May 1, 2015: A conversation with Robert S. DiPaola, MD, director of Rutgers Cancer Institute of New Jersey, which is a member of the Big Ten Cancer Research Consortium. Q: How do you think cancer research will change in the next 10 or 20 years? Over the last 20 years, the development of powerful new technologies was instrumental in what we have come to understand about the complexity and heterogeneity of cancer, from the role of genetic mutations to the behavior of our immune systems. The accomplishments of the last 20 years, more than any other period in cancer research, have set the stage for remarkably accelerated progress over the next 20 years, by teams that push the limits of what we imagined... Read More
April 17, 2015: Each month, the Big Ten Cancer Research Consortium highlights advances in research and treatment led by our member institutions. Following are recent developments across the consortium: Read More
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