Q: What kind of impact do you see the Big Ten Cancer Research Consortium having on cancer clinical trials?
Conquering cancer requires impactful research that is efficiently implemented and evaluated in clinical trials that are timely, appropriately designed, and skillfully performed and analyzed. This requires team effort.
Collaborating with other institutions allows for a broader and deeper brain trust while allowing the efficient testing of novel concepts and approaches in a more representative patient population. The synergist interactions, the collaboration, the implementation — all are aimed at one ultimate goal: Making a real difference for patients and their families. Read More
March 25, 2015: Big Ten cancer centers continue to make advances in cancer research and treatment. In this edition of Across the Consortium, we highlight research from our member institutions in colorectal, prostate, brain, ovarian, and other cancers; we celebrate the generosity of the Hirair and Anna Hovnanian Foundation, whose gift to the University of Michigan Comprehensive Cancer Center will help researchers establish the world's most comprehensive genomic analysis of adrenal cancers; we see once again what is possible when state legislatures get behind cancer research; and we applaud our member institutions and investigators who have achieved recent accolades and honors, of which only a few are mentioned in this article. Read More
March 2, 2015:A conversation with Leonidas Platanias, MD, PhD, director of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, which is a member of the Big Ten Cancer Research Consortium.Q: What kind of impact do you see the Big Ten Cancer Research Consortium having on cancer clinical trials? Our member institutions each have unique strengths and resources; the Big Ten Cancer Research Consortium (Big Ten CRC) provides the necessary structure to use those resources to the best advantage and expedite the development of effective, innovative clinical research. The consortium’s ability to streamline processes from clinical trial design to implementation expands... Read More
March 1, 2015: In this month's Q&A, Big Ten Cancer Research Consortium (Big Ten CRC) Administrative Headquarters addresses common questions related to monitoring. Monitoring staff at Big Ten CRC Administrative Headquarters will perform risk-based monitoring as outlined in our Data Monitoring Plans. Site monitoring is an essential part of the Big Ten CRC's ability to successfully run trials. Monitoring staff will source verify critical data elements in the patient charts to what is entered into the OnCore database. Critical data is identified as data supporting the primary and secondary objectives (e.g., eligibility, treatment data, disease evaluations, adverse events, serious adverse events, specified tests, etc.). Read More
Feb. 16, 2015: Insightful questions lie at the root of every advance in cancer research and improvement in patient care: What causes cells, as they become cancerous, to switch from aerobic metabolism to glycolysis, which does not require oxygen? How might a more complete understanding of a tumor's "onco-ecosystem" change the way we treat disease? Where will precision medicine and immunotherapy take us in the future? These are just a few of the questions currently being explored at Big Ten cancer centers. Read More
Feb. 1, 2015:A conversation with Anas Al-Janadi, MD, medical director of the Michigan State University Breslin Cancer Center, which is a member of the Big Ten Cancer Research Consortium.Q: What does the Michigan State University College of Human Medicine Breslin Cancer Center’s membership in the Big Ten Cancer Research Consortium mean for the patients you and your colleagues serve? Cancer is a devastating disease, and the fight against cancer can only be won by teaming up to fight this merciless enemy. Our patients now can have the cutting edge research that is expected to be created and launched by the consortium members. The diversity and unique strength of each institution will now come... Read More
Feb. 1, 2015: In this month's Q&A, Big Ten Cancer Research Consortium (Big Ten CRC) Administrative Headquarters addresses common questions related to correlative research. In what aspects of a clinical trial are correlative research managers at Big Ten CRC Administrative Headquarters able to assist? As clinical trials continue to increase in complexity and further emphasize translational science, the collection of correlative specimens and the succeeding specimen analysis becomes ever more important. Read More
Jan. 19, 2015: We begin a new year with recent highlights from each member institution of the Big Ten Cancer Research Consortium. From new discoveries in our understanding of RNAs to re-emerging ideas about Vitamin C; from initiatives that focus on our communities at home to those that stretch across continents, Big Ten cancer centers continue to innovate and inspire. Here’s to a promising new year across the consortium! Read More
Jan. 1, 2015:A conversation with Robert A. Winn, MD, interim director of the University of Illinois Cancer Center, which is a member of the Big Ten Cancer Research Consortium.Q: What kind of impact do you see the Big Ten Cancer Research Consortium having on cancer clinical trials? On our own, we each have characteristics that demonstrate who we are individually and in the context of our institution. In the context of the Big Ten CRC, our consortium harnesses the clinical expertise of 12 leading cancer centers specifically related to breast, GI, GU, GYN, hematologic, melanoma, and thoracic malignancies. Additionally, this is a fascinating time to be conducting cancer clinical trials:... Read More
Dec. 31, 2014: As the year comes to a close, the Big Ten Cancer Research Consortium would like to thank each of our member institutions for making 2014 a year of outstanding accomplishments. Hard work and a spirit of collaboration have underscored a number of significant milestones that are worthy of celebration. Consider just a few examples of what we have accomplished together: Read More
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