Big Ten cancer centers are making tremendous strides in tackling some of the toughest questions in cancer research. In this month’s edition of “Across the Consortium,” we highlight advances in leukemia, prostate cancer, ovarian cancer, lung cancer, and new technologies and discoveries that could improve outcomes across many cancers. Behind these advances in research at Big Ten cancer centers are academic physicians and scientists who are not only brilliant in their fields, but also committed to patient advocacy and disease prevention.
Here are a few recent highlights across the consortium:
Dec. 4, 2014: In this month's Q&A, Big Ten Cancer Research Consortium (Big Ten CRC) Administrative Headquarters addresses common questions related to regulatory and safety. What are the responsibilities of Big Ten CRC regulatory managers? Big Ten CRC regulatory managers assist with all aspects of regulatory issues related to Big Ten CRC research, including interactions with consortium members, institutional review boards, and regulatory agencies. Regulatory services include: Read More
Dec. 1, 2014:A conversation with George Weiner, MD, director of Holden Comprehensive Cancer Center at the University of Iowa and the C.E. Block Chair of Cancer Research and professor of internal medicine at the University of Iowa. Dr. Weiner has led a statewide collaborative to reduce the burden of cancer in Iowa, served on committees within the National Cancer Institute, and just began a two-year term as president of the Association of American Cancer Institutes (AACI), which comprises 92 leading cancer research centers in the United States.Q: What kind of impact do you see the Big Ten Cancer Research Consortium having on cancer clinical trials? Every one of our institutions has an outstanding group... Read More
Nov. 14, 2014: Today, the Big Ten Cancer Research Consortium introduces a new monthly feature highlighting news from our member institutions. We are proud to highlight each of our members, as we work together to improve the lives of all patients with cancer. Several Big Ten CRC member institutions were profiled in US Airways Magazine’s October issue in an extensive feature on the Association of American Cancer Institutes. The featured institutions include the University of Illinois Cancer Center, the University of Iowa Holden Comprehensive Cancer Center, the Read More
Nov. 1, 2014:A conversation with Douglas Yee, MD, director of the Masonic Cancer Center, which is a member of the Big Ten Cancer Research Consortium.Q: What strengths does the Masonic Cancer Center bring to the consortium? At the University of Minnesota and at the Masonic Cancer Center, there is a very collaborative atmosphere. We act collectively with the goal to change cancer outcomes, versus looking to finish a task solely on our own. The leadership here will bend over backwards to help each other because that ultimately helps patients. For example, I work mainly on breast cancer, and a colleague of mine focuses on HIV. He has studied mechanisms of... Read More
Oct. 1, 2014:What are the responsibilities of Big Ten CRC project managers? Big Ten CRC project managers coordinate and supervise the clinical trial from concept to close out. They serve as the main point of contact with pharmaceutical companies, physicians, and site staff. Project managers train all study staff on each protocol through a Site Initiation Visit (SIV). They also create and maintain a Study Procedures Manual (SPM) for each study. Read More
Oct. 1, 2014:A conversation with Timothy L. Ratliff, PhD, Robert Wallace Miller Director of the Purdue University Center for Cancer Research, which is a member of the Big Ten Cancer Research Consortium.Q: What kind of impact do you see the Big Ten Cancer Research Consortium having on cancer clinical trials? The collaborative interactions among Big Ten cancer centers will enable more rapid testing of new therapeutics. In truth, the whole is greater than the parts. By combining forces, multiple institutions will participate in clinical studies, patient accrual will occur more briskly and, therefore, outcomes will be determined more rapidly. Read More
Sept. 1, 2014:What is the process for submitting a budget with the LOI to the funder? The process begins with the Principal Investigator sending the proposed Letter of Intent (LOI) or protocol to Big Ten CRC Administrative Headquarters (Admin HQ). Each PI completes a brief questionnaire regarding the different elements that the budget should include. Once all necessary costs are added into the budget, Admin HQ will send the budget, along with the LOI or protocol to the funder for review. Admin HQ will negotiate the overall study budget directly with the funder, and the contracts department will then generate and negotiate a work order with each participating institution for payments that the sites will receive for participating in the trial. Read More
Sept. 1, 2014:A conversation with Howard Bailey, MD, interim director of the UW Carbone Cancer Center, which is a member of the Big Ten Cancer Research Consortium. Dr. Bailey, a professor of medicine, is a medical oncologist who specializes in gynecologic oncology and cancer prevention. He has led the development of three different state- and nation-wide clinical research networks to expand the access of “cutting edge” treatment for patients.Q: What kind of impact do you see the Big Ten Cancer Research Consortium having on cancer clinical trials? Without a doubt, the Big Ten Cancer Research Consortium will offer accelerated advancement when moving... Read More
Aug. 1, 2014:A conversation with Raymond J. Hohl, MD, PhD, director of Penn State Hershey Cancer Institute, which is a member of the Big Ten Cancer Research Consortium. Dr. Hohl joined Penn State Hershey from the Holden Comprehensive Cancer Center, University of Iowa, where he held the Holden Family Chair/associate chair of the Department of Internal Medicine, as well as associate director for clinical and translational research. At Penn State, he will hold academic appointments as professor in the departments of Medicine and Pharmacology.Q: What kind of impact do you see the Big Ten Cancer Research Consortium having on cancer clinical trials? The Big Ten Cancer Research Consortium... Read More
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