August 6, 2021: by Vijaya Bhatt, MBBS, MS Vijaya Bhatt, MBBS, MS, is an associate professor in the University of Nebraska Medical Center Division of Oncology/Hematology, Department of Internal Medicine, College of Medicine, and medical director of the Leukemia Program at UNMC.With the aging US population, we face the challenge of rising incidence of cancer in older adults. Older adults are at a higher risk of developing and dying from cancers. Several factors contribute to poor outcomes including cancer biology, multimorbidity, frailty, and social isolation, which has become worse during the COVID-19 pandemic. Older adults are also frequently not well represented in clinical trials; this poses additional challenges by creating a knowledge gap in understanding how to optimally treat older adults with comorbidities.... Read More
August 3, 2021: Purdue Center for Cancer Research (PCCR) scientist Philip Low, PhD, Presidential Scholar for Drug Discovery and Ralph C. Corley Distinguished Professor of Chemistry - Biochemistry (Department of Chemistry) at Purdue University. The latest research update from Dr. Low is the design, synthesis, and patenting of PSMA-617, an investigational PSMA-targeted radioligand therapy for metastatic castration-resistant prostate cancer. It began with a PCCR collaboration including Dr. Low, Timothy Ratliff, PhD, and Tom Gardner, MD, from Indiana University School of Medicine, who ran the first clinical imaging trial, funded by PCCR, to show the targeting agent was highly prostate cancer specific. Read More
July 22, 2021: In this month’s Across the Consortium, get to know some the cancer investigators in the Big Ten, what doctoral candidates and graduate students are researching, what publications and accolades have been shared with Big Ten researchers, and more. Read More
July 21, 2021: The Big Ten Cancer Research Consortium recently appointed Nancy Chan, MD (pictured right), a medical oncologist from Rutgers Cancer Institute of New Jersey, and Sneha Phadke, DO, MPH, (pictured left), a medical oncologist from University of Iowa Holden Comprehensive Cancer Center, as co-chairs of Big Ten CRC’s Breast Cancer Clinical Trial Working Group (CTWG). Their leadership supports collaboration and mentorship within the working group, as well as development of Big Ten CRC breast cancer clinical trials from conception to completion. CTWG co-chairs serve two-year terms that are... Read More
July 8, 2021: Murali Janakiram, MD, MS, a medical oncologist at the Masonic Cancer Center, University of Minnesota, and Attaya Suvannasankha, MD, a medical oncologist at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center, have been named co-chairs of the Big Ten Cancer Research Consortium’s Multiple Myeloma Clinical Trial Working Group. Dr. Janakiram is a graduate of Madras Medical College in Chennai, India. He completed his residency at Case Western University and MetroHealth Medical Center in Cleveland, Ohio, and his fellowship at Montefiore Medical Center,... Read More
July 8, 2021: Big Ten Cancer Research Consortium investigators are determined to give adolescents and young adults (AYA) a fair shot in overcoming cancer by addressing the systemic challenges that are often roadblocks to the best care, including access to cancer clinical trials. AYAs range in age between 15 to 39. According to the National Cancer Institute, an estimated 88,260 new cases of cancer will be diagnosed among AYAs and about 85% of AYAs diagnosed with cancer will survive their cancer beyond five years after their diagnosis, some left with chronic side effects and fertility issues. Incidence of cancer... Read More
July 7, 2021: Within the Big Ten Cancer Research Consortium, disease-specific Clinical Trial Working Groups are largely focused on developing novel therapeutics to treat and ultimately cure disease. The Big Ten CRC’s Population Science Working Group, led by co-chairs Sharon Manne, PhD, of Rutgers Cancer Institute of New Jersey and Electra Paskett, PhD, of The Ohio State University, has a different goal: To develop and implement population-based research within the Big Ten CRC. “The ultimate goal of our working group is to develop and implement research that reduces the cancer burden in the Big Ten,” said Dr. Manne (pictured left), Chief of Behavioral Sciences and co-Director of the... Read More
July 6, 2021: Big Ten Cancer Research Consortium investigators presented a poster highlighting the BTCRC-AML17-113 study during the American Association for Cancer Research Annual Meeting 2021. Led by John Quigley, MD, of the University of Illinois Cancer Center, the single-arm, open-label, multi-center phase Ib, dose-escalation study examines the safety and efficacy of gemtuzumab ozogamicin and venetoclax in patients with relapsed or refractory CD33+ acute myeloid leukemia. At the time the abstract was presented in April, researchers reported... Read More
June 29, 2021: During the month of July, the Big Ten Cancer Research Consortium highlights the Indiana University Melvin and Bren Simon Comprehensive Cancer Center, and cancer center member Paul Christian Mayor, MD, MS, FACOG. Paul Christian Mayor, MD, MS, FACOG Assistant Professor of Clinical Obstetrics and Gynecology Indiana University School of Medicine Educational Background Medical Degree: Medical College of Georgia, Augusta University Residency: Indiana University School of Medicine Fellowship: Roswell Park Comprehensive Cancer Center Read More
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